同源重组通过将基因的3'端(从第3外显子或1个内含子开始,具体取决于剪接变异)替换为lacZ报告基因座(包含Kozak序列和ATG起始密码子),以及一个由loxP序列 flank的诺卡因抗性基因座。(来源:J:204277)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NTac)F1
Targeted
插入,基因内删除
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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