L1L2_Bact_P cassette被插入到染色体9的54367995号位置,位于关键exon 7的上游。该 cassette包含FRT位点、lacZ序列和一个loxP位点。FRT位点后面跟着由人类β-actin启动子驱动的neomycin抗性基因,接着是SV40polyA,然后是一个第二个FRT位点和第二个loxP位点。第三个loxP位点位于exon 7下游的54368954号位置。通过Flp介导的重组,lacZ序列和neo cassette被移除,exon 7被标记为可翻转。(来源:J:217623)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
插入
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部