使用了MHPP352i17这个MICER载体(同源区域16:74930370-16:74937378 Mb,基于GRCm38/mm10的小鼠基因组),以及一个未指定的MICER载体,将loxP位点插入到了Lipi附近和Hunk的远端。通过Cre介导的重组,loxP位点所标记的序列被复制了(来源:J:227899)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
Duplication, Insertion
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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