MICER vectors MHPP323h04 (16:90563769-16:90577148 Mb; mouse assembly GRCm38/mm10) and MHPN219i02 (16:93054020-16:93062456 Mb) introduced loxP sites proximal to Mis18a and distal to Runx1. Cre-mediated recombination duplicated the sequence floxed by loxP sites. (J:227899)