这个构建包含CAG启动子、一个超激活的Sleeping Beauty响应型转座子-停止子元件的单拷贝,以及DsRed cassette,通过在携带Col1a1tm13(neo/hygro*)Jae的ES细胞中使用RMCE技术插入。超激活的Sleeping Beauty驱动的转座会导致报告基因的表达。(引用:J:217487)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
24
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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