(条件等位基因)(Dchs2)最初通过在Dchs2编码区域的最后一个外显子周围插入loxP位点实现,该区域包括其跨膜和细胞内部分。通过与一种能激活germline的删除-Cre小鼠品系[Tg(CMV-cre)1Cgn]杂交,产生了携带这种遗传性缺失(Dchs2)的实验鼠。(来源:J:226938)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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