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中文
带有Ccdc155tm1a(KOMP)Wtsi条件性突变基因的老鼠与携带Tg(Zp3-cre)93Knw转基因的C57/B6动物杂交，以删除5-8号染色体的外显子，导致框移并产生在4号染色体3'端后36个bp处的终止密码子。杂合子雄性老鼠经过Cre基因剔除后培育，并作为杂合体保留。定量RT-PCR和 Western blot对整个睾丸匀浆的分析确认了纯合子突变雄性中mRNA和蛋白质的完全缺失。杂合子雄性的睾丸样本显示mRNA和蛋白质水平约有50%的中等水平。(来源：201813)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
