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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Cidec
tm1.1Gonz
Alias:
Fsp27
F
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基础信息
表型特征
文献报道
这个靶向载体包含了exon 2上游的loxP位点,接着是一个由FRT引导的诺卡因选择标记,后面跟着loxP在exon 3下游。通过Flp介导的重组,FRT引导的诺卡因标记被移除,使得exons 2和3被留下了loxP位点。(来源:J:226899)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5699259
(C57BL/6J x 129S4/SvJae)F1
Targeted
插入
--
1
1
3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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