这个靶向载体插入了a基因座,包含CAG启动子、删除了STOP序列的Venus报告基因、三重F2A(口蹄疫2A肽序列的重复)、Sdk2基因、WPRE序列以及FRT引导的诺卡因抗性基因。通过Flp介导的重组,去除了诺卡因抗性基因。(来源:J:225578)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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