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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Sdk1
tm1.1(cre/ERT2)Jrs
Alias:
Sdk1
ce
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基础信息
表型特征
文献报道
将第一个编码外显子替换为一种可诱导的Cre重组酶基因(cre/ERT2),其带有三个串联的血红蛋白(HA)标签。Cre介导的重组移除了含荧光素酶耐药基因座。P30时的免疫组化结果显示视网膜中未检测到蛋白表达。(来源:J:225578)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5698881
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
--
3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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