KOMP导向的载体PG00184_Z_8_C04插入了FRT座、lacZ报告基因、loxP座、诺卡因抗性基因、FRT座和loxP座,这些位于第7外显子上游,以及第9外显子下游的第三个loxP座。通过Cre介导的重组,去除了选择性基因座和7至9号外显子。(来源:J:217589)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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