KOMP导向的载体PG00184_Z_8_C04插入了FRT位点、lacZ报告基因、loxP位点、诺卡因抗性基因座、再次的FRT位点和loxP位点,这些位于第7外显子上游,以及第9外显子下游一个第三个loxP位点。通过Flp介导的重组,移除了报告基因和选择性基因座,使得第7至9外显子区域被标记为可翻转。(来源:J:217589)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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