这只带有与人类第1589位exon 4中A到C替换(导致第443位His变为Pro的突变)的NLRC4基因cDNA,以及三个HA标签,由不变链启动子控制。生成了三条品系:1、2和3。品系1在脾脏中显示NLRC4水平大约有3.1倍于内源性的增加。(来源:J:219652)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
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插入
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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