在基因的3'末端插入了一盒包含CMV/tetO启动子和带有R140Q突变的人源IDH2基因cDNA的磁带。同时,还插入了一个FRT接头选择序列,随后通过FLP介导的重组被移除。(来源:J:217109)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion, Nucleotide substitutions
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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