4-10号外显子被替换成一个带有IRES-lacZ-SV40pA(β-半乳糖苷酶)标记和一个PGK-Neomycin-bGHpA选择座。北半球分析显示,这个等位基因编码的C端没有可检测到的转录本表达。N端与引入的lacZ基因一起表达。lacZ在支持细胞中表达。(来源:J:225512)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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