通过Flp介导的BC055324tm1a(EUCOMM)Hmgu等位基因的去除,删除了由启动子驱动的诺卡因选择标记片段和插入的lacZ报告序列,保留了loxP引导的关键外显子。有关此类IKMC等位基因的靶向策略的更多信息,请参阅http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml(来源:J:204739)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count