Ikbkb^M1Btlr

ENU mutagenesis induced a a T to C transition at base pair 22,666,020 (v38) on chromosome 8, or base pair 40,566 in the GenBank genomic region NC_000074, corresponding to residue 1,841 in the mRNA sequence NM_001159774 (variant 1) within exon 17 of 22 total exons and to residue 1,841 in the mRNA sequence NM_010546 (variant 2) within exon 17 of 21 total exons. The mutation results in an leucine (L) to proline (P) substitution at position 570 (L570P) in both isoforms of the protein. (J:225271)