锌指内切酶被用来产生了敲除等位基因。第431行中,6号外显子有一个16个碱基的缺失。 Western blot分析证实了没有蛋白质表达。(来源:J:225041)
查看原文 参与反馈
Zinc finger endonucleases were used to generate a knock-out allele. Lines 431 contains a 16 base pair deletion in exon 6. Western blot analysis confirmed the absence of protein expression. (J:225041)