ENU mutagenesis induced a C to T transition at base pair 4,333,965 (v38) on chromosome 18, or base pair 19,517 in the NC_000084 GenBank genomic region. The mutation corresponds to residue 1,250 in the mRNA sequence NM_008713 within exon 7 of 8 total exons. The mutation results in an arginine (R) to cysteine (C) substitution at position 376 (R376C) in the protein. (J:224668)