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中文
在exon 1插入了R3A和K5A突变，通过同源重组在intron 1插入了一个floxed neo cassette。exon 1的突变干扰了该蛋白与核小体重构和组蛋白去乙酰化酶复合体亚基的相互作用。通过Cre介导的重组移除了neo cassette。E13.5时期心肌组织的 Western blot分析显示，野生型、杂合子和纯合子突变心脏的蛋白水平相当。(来源：J:216295)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
