带有G12D突变的鼠源Kras基因,由tet操作子控制,其启动子和起始密码子之间插入了lox-stop-lox的同源重组 cassette。这种突变型Kras的表达依赖于Cre介导的停子 cassette 的删除。当不具体指明品系时,用#表示。如果指代多个品系或合子,也会用到#。来源:(J:186194)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
插入
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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