Fras1^b2b3323Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a C to T substitution at coding nucleotide 1228 in exon 12 of the cDNA (c.1228C>T, NM_175473). This changes the glutamine residue to a translation stop at position 410 of the encoded protein (p.Q410*). (J:175213)