从L限制的CD3+ CD4- CD8+细胞毒性T淋巴细胞(6C2克隆)中,我们获得了重排的Valpha4.1 JalphaNEW和Vbeta1.1 Jbeta2.5序列,这些细胞能识别HBsAg中28-39位的表位。这些TCR序列被克隆到TCR表达载体pTalpha和pTbeta中,并一起注射。主要研究者报告,16号和36号的创始株细胞在识别表位上没有差异。(引用J:213364)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
BALB/cByJ or C57BL/6J
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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