转基因小鼠品系,携带有5个拷贝的报告型酪氨酸酶构建(TYR5),之前已报道能恢复白化接收株的色素沉着,其表达量完全取决于整合位置和小鼠品系拷贝数。这种品系表达的TYR5水平适中,导致眼睛着色和全身灰色均匀的皮毛颜色。(来源:J:185183)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Hsd:NMRI
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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