这个靶向构建在第一个内含子引入了frt座标记的诺卡因抗性元件(neor),并在选择元件上游的loxP位点和下游的exon 2的loxP位点。选择元件可以通过flp重组酶进行删除,而neor和exon 2则通过cre重组酶可以被剔除。(来源:J:220670)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
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1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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