这个转基因构建包含一段经过从重复4到重复19以及C端删除改造的人类 dystrophin基因,通过鼠心肌特异性α肌动蛋白(Myh6或α-MHC)启动子驱动,生成一个微小的dystrophin cDNA(J:94077)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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