RMCE通过Gt(ROSA)26Sortm1Pmt将hygromycin抗性元件替换成一个含有人工启动子、终止子、neomycin抗性序列和Zfpm1序列的飞梭元件,以及human CD2报告基因(hCD2t)的插入。这项操作来自文献引用(J:215189)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129
Targeted
插入
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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