在exon 24上游插入了floxedneo抗药性基因座,然后在exon 24下游插入了另一个loxP位点。通过Cre介导的重组,去除了选择性基因座和exon 24。 Western blot结果显示,小鼠胚胎成纤维细胞中没有蛋白质表达(来源:J:221026)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NTac x 129S6/SvEvTac)F1
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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