这个靶向载体包含了反向排列的FRT引导的PGK-neo插件,以及在第2外显子下游的3' loxP位点,以及在第2外显子上游插入的另一个loxP位点。通过Flp介导的重组,FRT引导的neo插件被移除,留下第2外显子是可删除的(来源:J:220728)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
2
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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