插入了Velocigene cassette ZEN-Ub1导致了13号染色体(基因组Build37)11,438,4716-11,440,8600区段的23,885bp缺失,随后通过Cre介导的剔除操作移除了含诺瓦克林选择标记的 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count