插入了Velocigene cassette ZEN-Ub1导致染色体6(Genome Build37)12,468,9377-12,469,1086位点之间缺失了1,710个碱基对,随后通过Cre介导的去失操作移除了含诺瓦克林选择标记的 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count