这个转基因是通过小鼠的Nanog启动子驱动H2B-EGFP融合蛋白(编码人HIST1H2BB基因的序列,即histone 1 H2bb,带有C端增强绿色荧光蛋白基因)的表达,后面跟着一个内源性核糖体进入信号(IRES)、puromycin抗性基因座,以及猴病毒40(SV40)的polyadenylation位点。(来源:J:220299)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CBA/J x C57BL/6J
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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