Ddhd1^tm1.1Katn

The L1L2_gt2 cassette was inserted at position 45854541 of Chromosome 14 upstream of the critical exon 8 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre-mediated recombination removed exon 8. Western blot analysis confirmed the absence of protein expression in the testes. (J:212425)