Cre介导的重组移除了编码 tudor 区域的exons 5和6,以及hygromycin抗性基因座。 Western blot结果显示,对这种蛋白质的突变体有较低水平的表达。(来源:J:213823)
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Cre-mediated recombination removed exons 5 and 6, which encode the tudor domain, as well as the hygromycin resistance cassette. Western blot analysis confirmed low level expression of a mutant form of the protein. (J:213823)