Exon 10被修改,包含了Ntrk3编码序列,包括跨膜和细胞内区域(氨基酸431-824),插入了IRES、Cherry报告器、polyadenylation序列和一个被Cre介导的重组消除的选择性 cassette。产生的蛋白是Ntrk1的外区和Ntrk3的跨膜及内区的融合蛋白。(来源:J:210892)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
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1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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