Pdgfrb^b2b2903Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to C substitution at coding nucleotide 2498 in exon 18 of the cDNA (c.2498T>C, NM_001146268). this changes the leucine residue to proline at position 833 of the encoded protein (p.L833P). (J:175213)