在 intron 1 中插入了 loxP 立场,通过同源重组在 intron 3 中插入了 loxP 立场和带有 FRT 标记的新 cassette。通过 Flp 介导的重组移除了新 cassette。随后,Cre 介导的重组去除了 exons 2 和 3。(来源:J:210308)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
插入,基因内删除
--
1
4
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部