插入了Velocigene cassette ZEN-Ub1导致染色体7(基因组Build37)112885666-112891191位置之间出现了5526bp的缺失,随后通过Cre介导的去选系统删除了含诺美西林选择标记的 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count