克隆7B8来源于对TH17小肠CD4+T细胞进行筛选,这些细胞对SFB单特异性关联小鼠的粪便物质有反应。该受体能识别SFB的表位FSGAVPNK。克隆所关联的CDR3Vbeta14序列(AWSRSPSQNTLY)和Valpha15序列(AEGNMGYKLT)被插入到能由天然TCRalpha和-beta启动子/增强子驱动转录的载体中。(来源:J:212833)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
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9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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