一段来自大鼠cDNA 3'端的3.1kb片段被连接到EGFP后面,然后是一个polyadenylation信号。接着,这段序列与小鼠基因的exon 8中的EcoRI酶切位点融合。同时,还插入了一个条件性荧光素-neomycin cassette,但随后在定向敲除的实验小鼠中被去除了。(来源:J:133999)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部