插入了Velocigene cassette ZEN-Ub1导致了染色体12(Genome Build37)上8,647,7315-8,649,0835位置之间13,521bp的缺失,随后通过Cre介导的剔除操作移除了新霉素选择 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count