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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gnai2
tm2.1Rneu
Alias:
Galphai2
fl-G184S
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基础信息
表型特征
文献报道
基因的5-9外显子由loxP座 flank,下游跟着一个带有G184S突变的额外5号外显子副本。一个3'端带有FRT座的诺卡因抗性 cassette被放置。通过FLP介导的重组移除了FRT座的neo cassette。(来源:J:217517)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5614236
129/Sv
Targeted
插入
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1
4
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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