One loxP site was inserted upstream of exon 1 and a second loxP site followed by an FRT flanked PGK-neomycin cassette was inserted in a nonconserved region of intron 1. The selection cassette was subsequently removed by expression of flp recombinase. (J:217144)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count