在Lmbr1基因的第五内含子下游,插入了一个由loxP位点引导的lacZ和诺卡因抗性基因元件,同时通过同源重组删除了该区域除了第一个ETS结合位点之外的所有部分。剩下的一个ETS1/GABPA结合位点被变异,以阻止ETS1/GABPA的绑定。(来源:J:208849)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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