将一盒磁带插入由CAG启动子、内含子、可删除终止序列、连接到ERT2元件的 mouse Foxn1 基因cDNA、插入了IRES和GFP序列的位点。需要通过Cre介导的重组来激活蛋白表达。在tamoxifen存在时,蛋白活性与内源性蛋白相似。(来源:J:208852)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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