在exon 4的上游插入了loxP位点,通过同源重组,随后插入了floxed剪接接受体位点、内含子插入序列(IRES)和Betageo元件,这些位于exon 5的下游。通过Cre介导的重组,exons 4和5,以及选择性标记元件都被去除了。(来源:J:208261)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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