通过Cre介导的父本Gdpd5tm1a(EUCOMM)Hmgu等位基因的去除,去除了驱动诺卡因选择座的启动子,并可能保留了插入的lacZ报告序列。欲了解针对此类IKMC等位基因的其他靶向策略,请访问http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml(来源:J:204739)。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count