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第三外显子被增强型绿色荧光蛋白基因替换。定量实时PCR证实了纯合子中Prnp mRNA的缺失，以及杂合子中水平较低，大约为野生型的50-60%。在大脑的不同区域以及星形胶质细胞中，GFP表达得到了确认。(来源：J:215179)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
