设计了一种靶向载体,它包含了一个FLAG/生物表位标签和一个由FRT序列引导的诺卡因抗性(neo)基因座,这个基因座位于内源性Rbpj终止密码子之后,并位于3' UTR上游。通过FLP介导的重组,FRT引导的neo基因座被去除了(来源:J:185868)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入
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1
2
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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