The transgene contains 9.0 kb of upstream sequence from the rat tyrosine hydroxylase gene, the second intron of the rabbit beta-globin gene, the EGFP coding sequence and the rabbit beta-globin and SV40 polyadenylation signals. GFP expression is observed in dopaminergic neurons in the embryonic ventral mesencephalons and in the substantia nigra of the adult midbrain. (J:186830)